Partners completed measures of marital functioning, depression, hopelessness, empathic caregiving (patient), and caregiver burden (caregiver) before randomization at baseline (T0), post-intervention (T1), and 3-month post-intervention (T2). Data were analyzed using three-way analyses of covariance; main effects were treatment, patient status, and sex. Multilevel modeling was also employed. Results At T1, INT group led to significant improvement in marital functioning (p?=?0.0001) and patients’ experience of caregiver empathic care (p?=?0.02) versus CTL group. Effect sizes for these differences

were in the large range (d?=?1.00). In both groups, patients showed a marginally higher mean score for marital functioning compared with caregivers [INT: BAY 11-7082 order M?=?56.3, standard deviation (SD)?=?4.6 vs M?=?54.3, SD?=?4.5; CTL group: M?=?43.4, SD?=?10.3 vs M?=?42.4, SD?=?6.8, respectively]. At T2, results were maintained. Conclusions The effectiveness of and adherence to the EFT couple intervention for patients facing advanced cancer selleck products were demonstrated in this study. Larger randomized control trials are needed to confirm these findings. Qualitative studies may help to further understand the mechanism by which such an intervention may act. Copyright (c) 2011 John Wiley & Sons, Ltd.”
“We examined how preoperative

urodynamic findings are related to the urinary problems following surgical repair of pelvic organ prolapse (POP).

The clinical records of 87 women who underwent surgery for POP were reviewed retrospectively. Preoperatively, cough stress test and urodynamic selleckchem testing, including pressure-flow study, were performed with prolapse reduction. Postoperative evaluation included uroflowmetry, postvoid residuals,

and symptom assessment using questionnaires.

A cough stress test with simple filling was sufficient for diagnosis of occult stress urinary incontinence (SUI). The presence of detrusor overactivity was a good predictor of postoperative persistence of urgency and urge urinary incontinence. Postvoid residuals (PVR) largely increased immediately after surgery, but usually recovered within 1 month. Poor detrusor contractility was the best predictor of large PVR occurrence.

Preoperative urodynamic evaluation of SUI and detrusor function was useful for predicting postoperative urinary conditions in POP patients. Its cost-effectiveness remains to be examined.”
“The remote plasma deposition of hydrogenated amorphous carbon (a-C:H) thin films is investigated by in situ spectroscopic ellipsometry (SE). The dielectric function of the a-C:H film is in this paper parametrized by means of B-splines. In contrast with the commonly used Tauc-Lorentz oscillator, B-splines are a purely mathematical description of the dielectric function.

The selective location of the maleated copolymers Vactosertib solubility dmso in one phase or at interface accounted for the different toughening effects of the maleated copolymer, which is closely related to their molecular structure and composition. SEBS-g-MA was uniformly dispersed in PPO phase and greatly toughened PPO/PA6 blends even at low temperature. MBS-g-MA particles were mainly dispersed in the PA6 phase and around the PPO phase, resulting in a significant enhancement of the notched Izod impact strength of PPO/PA6 blends from 45 J/m to 281 J/m

at the MBS-g-MA content of 20 phr. In comparison, the ABS-g-MA was mainly dispersed in PA6 phase without much influencing the original mechanical properties of the PPO/PA6 blend. The different molecule structure and selective location of the maleated copolymers in the blends were reflected by the change of rheological behavior as well. (C) 2009 Wiley Periodicals, Inc. J Appl Polym Sci 115: 3385-3392, 2010″
“Background The purpose TH-302 mw of this study was to examine how young adult cancer patients make sense of their experiences with cancer.

Methods Semi-structured

interviews were conducted with patients at an urban tertiary care center

Results The sample for this study included 15 young adult cancer survivors. The ages of the participants ranged from 18 to 30years. The sample was 67% female (n=10) and 33% male (n=5). The sample was 87% Caucasian (n=13) and 13% Hispanic (n=2). Fifty-three percent of the participants were between ages 18 and 23years (n=8), and 47% of the participants were between ages 24 and 30years (n=7). Three themes emerged from the data: selleck intrapersonal change, interpersonal interactions, and role and identity in the hospital and the community. As they inevitably lose control in their lives, young adult patients seek to return to a familiar lifestyle that they consider as normal’. The formation of a revised identity and redefined set of norms allows the patients to regain control and express their individualism.

Conclusions This study contributes to our knowledge of the experiences

of young adult cancer patients and survivors. The findings serve to inform young adults, caregivers, and health professionals on coping with illness and its aftermath. Copyright (c) 2012 John Wiley & Sons, Ltd.”
“A model mixture (containing a-linolenic acid as interfering substance) for polychlorinated biphenyls (PCBs) and organochlorine pesticides determination was subjected to clean-up with various solid-phase extraction (SPE) columns. Octadecylsilyl (C-18), graphitised non-porous carbon (Envi-Carb), aminopropyl (NH(2)), Florisil and Alumina SPE sorbents were evaluated. The relative sample clean-up provided by these SPE columns was evaluated using gas chromatography with electron capture detection (GC-ECD).

The most frequent maternal complications were spontaneous preterm labor (56%), premature rupture of membranes (28.9%), anemia (24.4%) and preeclampsia (20.4%). Triplets conceived by assisted reproductive techniques were significantly more likely to develop spontaneous preterm labor than spontaneous pregnancies (60% vs. 40%, respectively; p = 0.045). Conclusions: Triplets have a very high risk of maternal complications such as preeclampsia. Moreover, the presence of spontaneous preterm labor is more AZ 628 frequent in triplets conceived by assisted reproductive techniques than in those spontaneously conceived.”
“Introduction. We investigated

the contribution of aldosterone synthase CYP11B2 polymorphism (C-344T) to the age-related changes in blood pressure in stroke patients.

Subjects and methods. Study subjects comprised 329 stroke patients (121 normotensive, 208 hypertensive) and 444 healthy controls. Genotyping was done by PCR-RFLP, and the contribution of CYP11B2 polymorphism to the risk of stroke was analysed by regression analysis.

Results. The T allele, and CT, TT, and CT + TT genotypes, independently of sex and age, were significantly associated with

increased stroke risk. Varied distributions of CYP11B2 genotypes were noted among patients with respect to gender, age and hypertension status, being pronounced in hypertensive patients. Both systolic and diastolic blood pressure were positively correlated with the presence of

T allele. Mean systolic and diastolic selleck products blood pressure were significantly higher among young (< 60 years) CT and TT genotype carriers. Regression NU7441 solubility dmso analysis confirmed the positive association of

CT and TT genotypes and systolic blood pressure, and the negative association of diastolic blood pressure with odds of stroke development. Taking

normotensive patients as reference, regression analysis identified TT genotype, age and female gender to be independently associated with increased odds of stroke.

Conclusion. Compared to CC genotype, CT and TT CYP11B2 genotypes are independently associated with increased stroke index.”
“Aim: Based on a maternal observation, we aimed to evaluate the treatment effectiveness of guaiazulene (GA) containing local pomade in the high-risk neonates with recalcitrant diaper dermatitis (RDD). Methods: We included 30 NICU patients of RDD, with level II-III aged between 22 and 67 days. Study group patients (n = 20) were treated with GA containing local pomade (0.05 g/100 g). Control group consisted of patients who had extended antifungal treatment. A visual scale was used to assess the response to treatment at the end of a week. Scoring was done at the beginning of the treatment, on the first, third and seventh days. Results: Statistically significant differences in visual scores were determined between the two groups at the initial and following days of the treatment. In study group, improvements at the first and third days of the treatment were better than those of control group.

Baseline clinical, biochemical, and echocardiographic data, indices of dialysis adequacy, and peritoneal transport rate were reviewed retrospectively. The clinical outcome was the occurrence of a CVE.

Results: Mean duration of follow-up was 28 (range 6 – 70) months. A CVE Smoothened Agonist concentration was observed in 33 patients

(11.3%). The 1-, 3-, and 5-year cumulative incidences of CVEs were 4.0%, 13.7%, and 27.5%, respectively. Although multiple variables were correlated with the prevalence of a CVE in the univariate analysis, hs-CRP, PP, and comorbidity remained significant after adjustment: hs-CRP: odds ratio (OR) 4.09 (1.53 – 10.95), p = 0.005; PP: OR 2.79 (1.26 – 6.17), p = 0.012. PP and hs-CRP, which were not intercorrelated U0126 solubility dmso in our data, combined adversely to increase the incidence of CVEs. The incidence of CVEs increased with the number of risk factors, which included high hs-CRP, high PP, and the presence of comorbidity (no risk factor, 0%; 1 risk factor, 1.5%; 2 risk factors, 30.8%; 3 risk factors, 53.9%).

Conclusions: Our study suggests that measurements of hs-CRP and PP at the start of PD may be helpful in predicting

the development of CVEs in the course of treatment with PD.”
“Staphylococcus aureus peritonitis is a serious complication of peritoneal dialysis (PD). Since reports of the course and treatment of S. aureus peritonitis have generally been limited to small, single-center studies, the aim of the current investigation was to examine the frequency, predictors, treatment, and clinical outcomes of this condition in all 4675 patients receiving Epigenetic Reader Do inhibitor PD in Australia between 1 October 2003

and 31 December 2006. 3594 episodes of peritonitis occurred in 1984 patients and 503 (14%) episodes of S. aureus peritonitis occurred in 355 (8%) individuals. 273 (77%) patients experienced 1 episode of S. aureus peritonitis, 52 (15%) experienced 2 episodes, 19 (5%) experienced 3 episodes, and 11 (3%) experienced 4 or more episodes. The predominant antibiotics used as initial empiric therapy were vancomycin (61%) and cephazolin (31%). Once S. aureus was isolated and identified, the prescription of vancomycin did not appreciably change for methicillin-sensitive S. aureus (MSSA) peritonitis (59%) and increased for methicillin-resistant S. aureus (MRSA) peritonitis (84%). S. aureus peritonitis was associated with a higher rate of relapse than non-S. aureus peritonitis (20% vs 13%, p < 0.001) but comparable rates of hospitalization (67% vs 70%, p = 0.2), catheter removal (23% vs 21%, p = 0.4), hemodialysis transfer (18% vs 18%, p = 0.6), and death (2.2% vs 2.3%, p = 0.9). MRSA peritonitis was independently predictive of an increased risk of permanent hemodialysis transfer [odds ratio (OR) 2.11, 95% confidence interval (CI) 1.17 - 3.82] and tended to be associated with an increased risk of hospitalization (OR 2.00, 95% CI 0.96 – 4.19).

The modification VX-765 Apoptosis inhibitor dramatically decreased the surface area of the HNTs. The property study of the HNTs grafted with P-SBA focused on the dispersion behavior in the biphase system. The results show that the grafted HNTs dispersed stably in the water/cyclohexane biphase system and were a potential emulsifier. (C) 2010 Wiley Periodicals, Inc. J Appl Polym Sci 117: 3054-3059, 2010″
“Objectives: To evaluate the efficacy and safety of using hepatitis B immunoglobulin (HBIG) during pregnancy to prevent hepatitis B virus (HBV) mother-to-child transmission (MTCT).

Methods: We systematically reviewed the effect of HBIG in decreasing

HBV MTCT from randomized controlled trials (RCTs) carried out between January 1990 and December 2008, in English and Chinese languages. Multiple databases were searched, and experts in this field were contacted. The methodological quality of each RCT was assessed by the Jadad score. We abstracted data on HBV intrauterine infection, MTCT, treatment methods, newborn immune prophylaxis methods, and adverse learn more effects. A Mantel-Haenszel random-effects model was employed for all analyses using odds ratios (OR) and 95% confidence intervals (95% CI).

Results: Five thousand nine hundred newborns of asymptomatic hepatitis B surface antigen (HBsAg)seropositive mothers from 37 qualified RCTs were included. Compared with the control

group, newborns in the HBIG group had a lower intrauterine infection rate (indicated by HBsAg as OR 0.22, 95% CI [0.17, 0.29], from 32 RCTs; indicated by HBV DNA as OR 0.15, 95% CI [0.07, 0.30], from 13 RCTs; p < 0.01 for both) and a higher protection rate (indicated by hepatitis B surface antibody (HBsAb) as OR 11.79, 95% CI [4.69, 29.61], from 15 RCTs; p < 0.01). The same trend was found in MTCT by the time of 9-12 months after birth, indicated by HBsAg (OR 0.33, 95% CI [0.21, 0.51], from nine

RCTs; p < 0.01) and HBsAb (OR 2.49, 95% CI [1.55, 4.01], from 11 RCTs; p < 0.01). HBIG appears to be safe, but a few RCTs have reported adverse SBI-0206965 ic50 events.

Conclusion: Multiple injections of HBIG in HBV carrier mothers with a high degree of infectiousness in late pregnancy, effectively and safely prevent HBV intrauterine transmission. (C) 2010 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.”
“Purpose: To determine whether perfusion abnormalities are depicted on arterial spin-labeling (ASL) images obtained in patients with normal bolus perfusion-weighted (PW) magnetic resonance (MR) imaging findings.

Materials and Methods: Institutional review board approval and written informed patient consent were obtained. This study was HIPAA compliant. Consecutive patients suspected or known to have cerebrovascular disease underwent 1.5-T brain MR imaging, including MR angiography, gradient-echo PW imaging, and pseudocontinuous ASL imaging, between October 2007 and January 2008.

“
“Chronic lymphocytic leukemia (CLL) is the most common leukemia in the western world. The mechanism the mechanism of the disease development still remains unrevealed. In recent years new unique molecular and clinical features of CLL have emerged leading to a unified hypothesis of CLL origin. Major progress in understanding CLL biology was made after

identification of mutational status of immunoglobulin variable heavy chain (IGHV) genes, which also improved prediction of patients’ clinical outcome. Preferential usage of IGHV genes has led to recognition of CLL-specific B cell receptors (BCRs), called stereotyped BCRs. Taken together, these data point to antigen stimulation of CLL progenitor cells. Studies on CLL antibody reactivity have shown affinity to molecular motifs on apoptotic cells and bacterial cell structures, supporting the current hypothesis of the selleck chemicals llc CLL pathomechanism. In this paper we have summarized information available to date regarding current theory of cellular origin and pathology of CLL.”
“Objective: To identify the technological contributions of the newer version of speech processor to the first generation of multichannel cochlear implant and the satisfaction of users of the new technology.

Among the new features available, we focused on the effect of the frequency allocation table, the T-SPL and C-SPL, and the preprocessing gain adjustments (adaptive dynamic range optimization).

Study Design: Prospective exploratory study.

Setting: PI3K inhibitor Cochlear implant center at hospital.

Patients: Cochlear implant users IACS-10759 ic50 of the Spectra processor with speech recognition in closed set. Seventeen patients were selected between the ages of 15 and 82 and deployed for more than 8 years.

Interventions: The technology update of the speech processor for the Nucleus 22.

Main Outcome Measures: To determine Freedom’s

contribution, thresholds and speech perception tests were performed with the last map used with the Spectra and the maps created for Freedom. To identify the effect of the frequency allocation table, both upgraded and converted maps were programmed. One map was programmed with 25dB T-SPL and 65dB C-SPL and the other map with adaptive dynamic range optimization. To assess satisfaction, SADL and APHAB were used.

Results: All speech perception tests and all sound field thresholds were statistically better with the new speech processor; 64.7% of patients preferred maintaining the same frequency table that was suggested for the older processor. The sound field threshold was statistically significant at 500, 1,000, 1,500, and 2,000 Hz with 25dB T-SPL/65dB C-SPL. Regarding patient’s satisfaction, there was a statistically significant improvement, only in the subscale of speech in noise abilities and phone use.

8%) patients. Minor complications were encountered in four (5.6%) patients. Percentage of hepatocyte necrosis was the only histological parameter that has significant discriminatory prognostic value, with no survivors having >75% necrosis without LT. In conclusions, TJLB is a safe technique for obtaining liver FG-4592 inhibitor tissue in both adult and pediatric patients with ALF. Histological characteristics, mainly etiological diagnosis and degree of hepatocyte necrosis may assist in clinical decision-making for need of LT in these patients.”
“We use scanning photocurrent microscopy

(SPCM) to investigate individual suspended semiconducting carbon nanotube devices where the potential profile is engineered by means of local gates. In situ tunable p-n junctions can be generated at any position along the nanotube axis. Combining SPCM with transport measurements allows a detailed microscopic study of the evolution of the band RG-7112 mouse profiles as a function of the gates voltage. Here we study the emergence of a p-n and a n-p junctions out of a n-type transistor channel using two local gates. In both cases the I – V curves recorded for gate configurations corresponding to the formation of the p-n or n-p junction in the SPCM measurements reveal

a clear transition from resistive to rectification regimes. The rectification curves can be fitted well to the Shockley diode model with a series resistor and reveal a clear ideal diode behavior. (c) 2011 American Institute of Physics. [doi: 10.1063/1.3645022]“
“Background: EX 527 Epigenetics inhibitor High-fat, low-carbohydrate diets are widely used for weight reduction, but they may also

have detrimental effects via increased circulating free fatty acid concentrations.

Objective: We tested whether raising plasma free fatty acids by using a high-fat, low-carbohydrate diet results in alterations in heart and brain in healthy subjects.

Design: Men (n = 16) aged 22 +/- 1 y (mean +/- SE) were randomly assigned to 5 d of a high-fat, low-carbohydrate diet containing 75 6 1% of calorie intake through fat consumption or to an isocaloric standard diet providing 23 +/- 1% of calorie intake as fat. In a crossover design, subjects undertook the alternate diet after a 2-wk washout period, with results compared after the diet periods. Cardiac 31 P magnetic resonance (MR) spectroscopy and MR imaging, echo-cardiography, and computerized cognitive tests were used to assess cardiac phosphocreatine (PCr)/ATP, cardiac function, and cognitive function, respectively.

Results: Compared with the standard diet, subjects who consumed the high-fat, low-carbohydrate diet had 44% higher plasma free fatty acids (P < 0.05), 9% lower cardiac PCr/ATP (P < 0.01), and no change in cardiac function. Cognitive tests showed impaired attention (P < 0.01), speed (P < 0.001), and mood (P < 0.01) after the high-fat, low-carbohydrate diet.

1070 +/- A 435 min, P < 0.001). Vaginal delivery rates

within 12 h were found to be significantly higher with misoprostol induction [n = 37 (66%) vs. n = 25 (44.6%); P = 0.02], whereas vaginal delivery rates in 24 h did not differ significantly between groups [n = 41 (73.2%) vs. n = 36 (64.2%); P = 0.3]. More subjects required oxytocin augmentation in dinoprostone group [n = 35 (62.5%) vs. n = 20 (35.7%), P = 0.005] and cardiotocography tracings revealed early decelerations occurring more frequently with misoprostol induction (10.7 vs. 0%, P = 0.03). Tachysystole and uterine hyperstimulation, mode of delivery, rate of cesarean sections due to fetal distress and adverse neonatal outcome were not demonstrated to be significantly different between groups (P = 1, P = 0.5, P = 0.4, P = 0.22, P = 0.5).

Using Torin 1 mouse vaginal misoprostol is an effective way of labor induction in term pregnant women with unfavorable cervices, since it is associated with a shorter duration LGX818 mw of labor induction and higher rates of vaginal delivery within 12 h. Misoprostol and dinoprostone are equally safe, since misoprostol did not result in a rise in maternal and neonatal morbidity, namely, tachysystole, uterine hyperstimulation, cesarean section rates and

admission to neonatal intensive care units as reported previously in literature.”
“Characteristics of beef patties with low-salt (0.5%) and low-fat (<10%) contents were studied during frozen storage as affected by addition

of Wakame seaweed (3%) and partial or total replacement of pork backfat with olive oil-in-water emulsion. Patties with Wakame presented less (P < 0.05) thawing and cooking losses and were softer (P < 0.05) than patties without seaweed. A softening effect (P < 0.05) induced by olive oil emulsion was observed only in seaweed-free patties. Lipid oxidation Selleck 3-Methyladenine and microbiological counts in reformulated products were not a limiting factor for frozen stability. Wakame incorporation increased (P < 0.05) mineral contents, but all products presented the same Na/K ratio. Observed changes in microstructure were associated with seaweed addition (formation of alginate chains). All products were judged acceptable by the sensory panel. In the course of frozen storage no important changes were found in the target properties due to the different treatments. (C) 2010 Elsevier Ltd. All rights reserved.”
“ObjectiveThe aim of this randomized controlled trial for patients with advanced cancer receiving radiation therapy was to determine the effect of a multidisciplinary intervention on spiritual quality of life (QOL) at the end of the intervention (week 4) and at two follow-up time points (weeks 26 and 52).

MethodsOne hundred thirty-one persons were randomized to either the intervention or control (forms only) groups. The intervention included six 90-min in-person sessions based on the physical, emotion, social, and spiritual domains of QOL.

For isothermal crystallization, the development of relative crystallinity with the crystallization time is analyzed by the Avrami equation with the exponent

n = 2.7. The relatively high content this website of secondary crystallization at higher crystallization temperature can be obtained due to the high mobility of UHMWPE chains. For nonisothermal crystallization studies, the Avrami theory modified by Jeziorny is used, and the result is found that the Avrami exponent n is variable around 5 and decreases slightly as the cooling rate decreases. In addition, the extent of secondary crystallization increases with increasing cooling rate. The calculated activation energies are 881 kJ/mol for isothermal crystallization obtained from the Arrhenius equation and 462 kJ/mol for nonisothermal crystallization from the Kissinger equation, respectively. (C) 2011 Wiley Periodicals, Inc. J Appl Polym Sci 122: 2442-2448, 2011″
“Study Design. A retrospective study

Objective. To classify the types and identify related factors on sagittal decompensation after corrective osteotomy selleck compound for lumbar degenerative kyphosis (LDK).

Summary of Background Data. There has been a skeptical view of surgical treatment of LDK owing to loss of sagittal balance

even after correction of kyphosis. However, there had been no report on the classification and risk factors of sagittal decompensation.

Methods. A total of 23 LDK patients who had undergone corrective osteotomy were enrolled. The mean follow-up period was 45.7 months. Radiographic parameters including sagittal balance, the cross-sectional area of paravertebral muscles, were analyzed. We classified the type of sagittal decompensation into thoracic (Group T) and lumbar decompensation selleck chemicals llc (Group L) with a reference line from the posterosuperior corner of the sacrum to the center of the T12-L1 disc. The type of sagittal decompensation was defined with the location of T1 and the reference line at the last follow-up radiographs.

Results. The mean number of fusion

segments was 7.7. Sagittal balance improved from 26.4 cm to 4 cm immediately after operation but deteriorated to 11.2 cm at the last follow-up. The decompensation was greater in Group T (11 cases) than in Group L (12 cases) (9.1 cm vs. 5.2 cm, P = 0.03). The comparative analysis showed significant differences between groups T and L in thoracic kyphosis at the last follow-up (Group T:L = 40.5 degrees:27.5 degrees, P = 0.04), preoperative thoracic kyphotic angle (Group T:L = 19.6 degrees:-1 degrees, P = 0.01), mean ratio of cross-sectional area of paravertebral muscles to intervertebral disc in T12-L1, and incidence of the preoperative compensatory thoracic lordosis (Group T:L = 27.3%: 100%, P = 0).

Conclusion. The mean sagittal decompensation after corrective osteotomy for LDK was 38.3%.

Result: Increased expression of IAPs in cancer tissues compared to surrounding nonneoplastic counterparts was observed in 67 cases (42.1%) for Livin, 50 cases (31.4%) for XIAP, and 68 cases (42.8%) for SMAC. A significant correlation was found between Tariquidar clinical trial Livin expression and tumor differentiation, and SMAC expression and tumor location. The recurrence-free and overall survival of patients with low Livin expression

were inferior to those of patients with high Livin expression (p=0.054 and 0.095, respectively). High XIAP expression was significantly associated with shorter progression-free survival (p=0.041). Conclusions: Our study demonstrated that altered expression of IAP family members, including Livin, XIAP, and SMAC, is frequent in colorectal carcinoma. This result suggests that high Livin expression and low XIAP expression may be a favorable prognostic implication related to patient survival.”
“In temporal lobe epilepsy (TLE) JAK drugs there may be functional abnormalities or structural lesions that can manifest as a central auditory processing disorder. which is defined

as a disorder in the recognition, discrimination, ordering, grouping, and localization of sounds, with emphasis on the processing of nonspeech sounds. We performed frequency pattern, duration pattern, and dichotic tests in 28 patients with TLE with normal hearing on pure tone audiometry. The scores on the frequency pattern, duration pattern, and dichotic tests were abnormal in 78.6, 57.1, and 20.6% of patients, respectively, with no significant differences with the laterality of TLE. Patients with hippocampal sclerosis performed significantly worse than patients

with normal MRI findings in frequency LY3039478 tests. Longer duration of epilepsy is negatively correlated with both the duration pattern and dichotic tests (P < 0.05). Our results suggest that patients with TLE may be at risk for impairment of central auditory processing, which is increased in patients with hippocampal sclerosis or a longer duration of epilepsy. (C) 2010 Elsevier Inc. All rights reserved.”
“The protein 14-3-3 sigma is involved in the regulation of cellular processes such as apoptosis, cell cycle progression and proliferation. Disruption of protein expression has been implicated in a number of malignancies. Here we examine the expression pattern of 14-3-3 sigma in breast cancer and specifically consider whether expression in ductal carcinoma in situ ( DCIS) lesions is predictive of disease outcome. We examined 14-3-3 sigma protein expression and localization using immunohistochemical staining on a high-density tissue microarray consisting of 157 invasive breast cancer patients. Statistical analyses were used to assess the correlation of 14-3-3 sigma expression with clinico-pathological parameters and patient outcome.