Thus, even though permeating and non-permeating solutes had the s

Thus, even though permeating and non-permeating solutes had the same effect on specific growth rates (Figure 1), these solutes affect cells in fundamentally different ways. Future work is now needed to test whether the responses to permeating and non-permeating solutes accurately simulate the responses to the solute and matric components of the total water potential, respectively, and to connect these responses with those observed in more realistic scenarios of soil desiccation.

Acknowledgements and funding We thank the European Community program FP7 (grant KBBE-211684) (http://​cordis.​europa.​eu/​fp7/​home_​en.​html) for financial support of this project. We thank Regina-Michaela Wittich for kindly providing strain RW1 and Jacques Schrenzel for helpful advice about cDNA labeling protocols. We thank the DNA Array Facility at the University of Lausanne for assistance with find more microarray analyses. Electronic supplementary

material PD173074 solubility dmso Additional file 1: Complete list of genes whose expression levels responded to short-term perturbation with sodium chloride or PEG8000 (FDR < 0.05, fold difference > 2.0). (XLSX 53 KB) Additional buy Talazoparib file 2: Complete list of genes whose expression levels responded to short-term perturbation with sodium chloride but not PEG8000 (FDR < 0.05, fold difference > 2.0). (XLSX 59 KB) Additional file 3: Complete list of genes whose expression levels responded to short-term perturbation with PEG8000 but not sodium chloride (FDR < 0.05, fold difference > 2.0). (XLSX 56 KB) Additional file 4: Complete list of genes whose expression levels

responded Bcl-w to long-term perturbation with PEG8000 (FDR < 0.05, fold difference > 2.0). (XLSX 57 KB) References 1. Hiraishi A: Biodiversity of dioxin-degrading microorganisms and potential utilization in bioremediation. Microbes Environ 2003, 18:105–125.CrossRef 2. Wittich RM, Wilkes H, Sinnwell V, Francke W, Fortnagel P: Metabolism of dibenzo- p -dioxin by Sphingomonas sp. strain RW1. Appl Environ Microbiol 1992, 58:1005–1010.PubMed 3. Wilkes H, Wittich R, Timmis KN, Fortnagel P, Francke W: Degradation of chlorinated dibenzofurans and dibenzo- p -dioxins by Sphingomonas sp. strain RW1. Appl Environ Microbiol 1996, 62:367–371.PubMed 4. Armengaud J, Happe B, Timmis KN: Genetic analysis of dioxin dioxygenase of Sphingomonas sp. strain RW1: catabolic genes dispersed on the genome. J Bacteriol 1998, 180:3954–3966.PubMed 5. Wittich RM: Degradation of dioxin-like compounds by microorganisms. Appl Microbiol Biotechnol 1998, 49:489–499.PubMedCrossRef 6. Halden RU, Halden BG, Dwyer DF: Removal of dibenzofuran, dibenzo-p-dioxin, and 2-chlorodibenzo-p-dioxin from soils inoculated with Sphingomonas sp strain RW1. Appl Environ Microbiol 1999, 65:2246–2249.PubMed 7. Harris RF: Effect of water potential on microbial growth and activity. In Water Potential Relations in Soil Microbiology. SSA Special Publication Number 9. Edited by: Parr JF, Gardner WR, Elliot LF.

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