The biopsies were re-evaluated according to the Banff 97 classification. The prognostic significance of donor risk factors and Chronic Allograft Damage Index (CADI) was analyzed.

We propose a new donor risk score, calculated as the count of positive risk factors from a defined set of factors in the medical history of the donor. This Flavopiridol price donor risk score predicts histological quality of the kidney, graft function, and survival. Transplantations from donors with donor risk score > 4 had significantly decreased graft survival compared to those with donor risk scores 0-4; the five-yr death-censored graft survivals were 83% vs. 93%, respectively. High donor CADI score (> 3) was associated with worse graft function and survival. Three-yr glomerular filtration rate declined from 82 to 49 mL/min with donor CADI increase from 0 to >= 4. Our results show that high donor risk score and CADI value reflect low functional reserve

and risk for poor graft outcome.”
“Extraction of the Richardson constant and Schottky barrier height from the current-voltage-temperature (I-V-T) characteristics of Schottky barrier contacts is greatly influenced by a variety of nonideal effects. Starting with an overview of the original Richardson plot and relevant modifications of the Richardson selleck kinase inhibitor plot, this article discusses limitations of previous analytical approaches that attempt to account for the effects of barrier height inhomogeneities on the extracted Richardson constant. A temperature-driven fundamental change in the current conduction in an inhomogeneous Schottky diode

from conduction dominated by low barrier height patches to conduction dominated by high barrier height regions is identified as a likely source for the bowing of the Richardson plot, and knowledge of which regime dominates the current transport is critical for accurate determination of the Richardson constant. A simple linear relation PF-02341066 ic50 between the effective Richardson constant and effective barrier height is described, and this recently-reported linear relation provides a consistent method for estimating the Richardson constant of inhomogeneous Schottky diodes when transport is primarily through high barrier height regions. The method is applied to I-V-T characteristics of Au/Ni/n-GaN Schottky diodes measured from 320-440 K. A homogeneous Richardson constant of 29 +/- 6 A cm(-2) K(-2) is extracted using the proposed approach and is in very good agreement with the theoretical value of 26.4 A cm(-2) K(-2). (C) 2011 American Institute of Physics. [doi: 10.1063/1.3530868]“
“The impact of obesity on long-term kidney transplant outcome has largely been studied in non-African American patients. This study seeks to determine differences in outcome between obese and non-obese patients after kidney transplantation, in a predominantly African American population. We reviewed 642 adult renal transplant recipients who received their transplants at SUNY Downstate Medical Center between 1998 and 2007.