rosmarinifolia. Thirty-eight percent of bands in this small population of B. ingramii were exclusively shared with B. rosmarinifolia. This covert hybridisation may have been an ancient event but may be responsible for contemporary declines in germination and establishment in B. ingramii. The conservation implications are amplified by the endangered status of B. ingraniii. Crown Copyright (C) 2009 Published by Elsevier Ltd. All rights reserved.”
“Acute intermittent porphyria is a metabolic disorder rarely seen in prepubertal children. A delay in diagnosis of acute intermittent porphyria is common because of variable

and nonspecific symptoms. We report an 8-year-old boy with right hemimegalencephaly and intractable seizures, who presented with dark-colored urine, hypertension, increasing lethargy, fluctuating seizures, and poor oral intake. PF-00299804 in vivo He subsequently developed hyponatremia secondary to syndrome of inappropriate antidiuretic hormone secretion. His urinalysis was negative for red blood cells, and a random urine porphobilinogen level was elevated. Further biochemical and molecular testing confirmed the diagnosis of acute intermittent porphyria. His antiepileptic medications were discontinued GPCR Compound Library and hemin administered, with dramatic clinical improvement. The diagnosis of acute intermittent porphyria was challenging because of

his underlying neurologic condition. This case highlights the variable

presentation of acute intermittent porphyria and emphasizes the importance of considering the diagnosis even in young patients with underlying neurologic conditions when they present with nonspecific neurovisceral symptoms or with unexplained neurologic deterioration.”
“A systematic study on the deformation mechanisms of molybdenum (Mo) nanowires (NWs) was conducted using molecular dynamics simulations. Both axial Selleck VX-680 orientation and wire thickness were found to play important roles in determining the deformation pathways. In the NWs with orientation < 110 >/111, full dislocation plasticity is referentially activated on 110 planes. For both < 100 >/110 and < 100 >/100 NWs, twinning is the dominant mechanism with 112 being the coherent twin boundaries. A progressive slip process leads to a uniform elongation of 41% and the < 100 > wire axis reorients to < 110 >. For < 100 >/100 NWs, the reorientation mechanism ceases to operate when the diameter d < 1 nm or d > 8 nm. The atomic chains are energetically preferred for ultrathin NWs after yielding due to the resemblance of the surface to the close-packed bcc planes, while multiple slip systems tend to be activated for larger NWs. Finally, a theoretical model is proposed to explain the underlying mechanism of size dependence of the yield stress. (C) 2011 American Institute of Physics. [doi:10.1063/1.