However, the association between these deficits has not been thoroughly examined. Methods: We studied 44 PD subjects and 17 age-matched controls. In PD subjects, symptoms were assessed with the Unified Parkinson’s Disease GSK1210151A supplier Rating Scale and the Hoehn and Yahr scale. Cognition in both groups was assessed by a neuropsychological battery. Olfactory identification and sensitivity was evaluated with the Sniffin’ Sticks (R) test and olfactory detection threshold, respectively. Results: PD subjects showed significant deficits in olfactory function and working memory, executive function, speed of information processing,
visuospatial skills and phonological verbal fluency tests when compared with the control group. Moreover, there was a significant correlation between olfactory sensory deficits and executive dysfunction. In PD patients with up to 12 months of motor symptoms, results were equivalent. Conclusion: Our preliminary results suggest a significant association between olfactory deficits and impairments of executive functions in PD. Copyright (C) 2012 S. Karger AG, Basel”
“Background: Due to ongoing rise in need for care for people with chronic diseases and lagging increase in number of care providers, alternative forms of care provision and self-management support are needed. Empowering patients
through an online care platform could help to improve patients’ self-management and reduce the burden on the healthcare system.
Methods: Access to laboratory results and educational modules on diabetes will be offered through a platform for subjects with type 2 diabetes mellitus treated in primary care. Differences JQ1 nmr in socio-demographic and clinical characteristics between subjects expressing interest vs. disinterest to use the platform will be explored. Platform usage will be tracked and compared. Patient satisfaction and quality of life will be measured by validated questionnaires and economic analyses will be performed.
Discussion: This study is designed to assess the feasibility of use of an online platform in routine primary healthcare for subjects with
type 2 diabetes mellitus in the Netherlands, and to study effects of use of the platform on treatment satisfaction, quality EPZ-6438 of life and clinical parameters. Although providing access to a online platform is not a novel intervention, usage and effects have not yet been studied in this patient population.”
“Obesity is an increasing health problem all over the world. Phytochemicals are potential agents to inhibit differentiation of preadipocytes, stimulate lipolysis, and induce apoptosis of existing adipocytes, thereby reducing the amount of adipose tissue. Flavonoids and stilbenoids represent the most researched groups of phytochemicals with regards to their effect on adipogenesis, but there are also a number of in vitro and in vivo studies with phenolic acids, alkaloids, and vitamins, as well as other plant compounds.