and Kavalci et al Conclusion Our results suggested that serum BN

and Kavalci et al. Conclusion Our results suggested that serum BNP was not an adequate marker for determination of an intracranial pathology in patients with minor head trauma. As to date conflicting results have been reported, further studies with larger

sample size should be followed in order to establish a possible link between serum BNP and minor head trauma. Limitation of the study Since the number of patients in the present study is too low, the power of the study fell short to draw any meaningful conclusion. Moreover, the patient number in Group 2 was even lower (14 patients). Despite these limitations, our study demonstrated that there was no significant difference between KPT-8602 supplier Group selleck 1 and 2 although all patients in the study had demonstrable intracranial lesions. Another limitation, We didn’t perform a serial BNP measurements because it

is expensive. References 1. Ingebrigtsen T, Romner B, Kock-Jensen C: Scandinavian guidelines for initial management of minimal, mild, and moderate head injuries. The scandinavian neurotrauma committee. J Trauma 2000, 48:760–766.PubMedCrossRef 2. Dietrich AM, Bowman MJ, Ginn-Pease ME, Kosnik E, King DR: Pediatric head injuries: can clinical factors reliably predict an abnormality on computed tomography? Ann Emerg Med 1993, 22:1535–1540.PubMedCrossRef 3. Poli-de-Figueiredo LF, Biberthaler P, Simao Filho C, Hauser C, Mutschler W, Jochum M: Measurement of S-100B for risk classification of victims sustaining minor head injury-first pilot study in Brazil. Clinics 2006, 61:41–46.PubMedCrossRef 4. Woertgen C, Rothoerl RD, Metz C, oxyclozanide Brawanski A: Comparison of clinical, radiologic, and serum marker as prognostic factors after Bromosporine solubility dmso severe head injury. J Trauma 1999, 47:1126–1130.PubMedCrossRef 5. Kavalci C, Durukan P, İlhan N, Güzel A: The value of serum MDA for the diagnosis of intracranial ınjury. Trakya Univ Tip Fak Derg 2008, 25:209–213. 6. Guzel A, Karasalihoglu S, Aylanç H, Temizöz O, Hiçdönmez T: Validity of serum tau protein levels in pediatric

patients with minor head trauma. Am J Emerg Med 2010, 28:399–403.PubMedCrossRef 7. Çevik Y, Durukan P, Erol FS, Yıldız M, İlhan N, Serhatlıoğlu S: Diagnostic value of bedside brain natriuretic peptide measurement in patients with head trauma. JAEM 2010, 9:21–25. 8. Sviri GE, Soustiel JF, Zaaroor M: Alteration in brain natriuretic peptide (BNP) plasma concentration following severe traumatic brain injury. Acta Neurochir 2006, 148:529–533.PubMedCrossRef 9. Lu DC, Binder DK, Chien B, Maisel A, Manley GT: Cerebral salt wasting and elevated brain natriuretic peptide levels after traumatic brain injury: 2 case reports. Surg Neurol 2008, 69:226–229.PubMedCrossRef 10. Stewart D, Waxman K, Brown A, Schuster R, Schuster L, Hvingelby EM, et al.: B type natriuretic peptide levels May Be elevated in the critically ınjured trauma patient without congestive heart failure.

Comments are closed.