Nucleic Acids Res 1997,25(15):3124–30.Adavosertib purchase PubMedCrossRef 15. Hori T, Guo F, Tanaka Y, Uesugi S: Design and properties of trans-acting HDV ribozymes with extended substrate recognition regions. Nucleic Acids Res Suppl 2001, (1):201–2. 16. Nishikawa F, Fauzi H, Nishikawa S: Detailed analysis of base preferences at the cleavage site of a transacting HDV ribozyme: a mutation that changes cleavage site specificity. Nucleic Acids Res 1997,25(8):1605–10.PubMedCrossRef 17. Corey DR: Telomerase inhibition, oligonucleotides, and clinical trials. Oncogene 2002,21(4):631–7. 10. Bisoffi M, Chakerian AE, Fore ML, Bryant JE, Hernandez JP, Moyzis RK, Griffith JK. Inhibition
of human telomerase by a retrovirus expressing find more telomeric antisense RNA, Eur. J. Cancer. 1998, 34(8): 1242–9PubMedCrossRef 18. Naka K, Yokozaki H, Yasui W, Tahara H, Tahara
E, Tahara E: Effect of antisense human telomerase RNA transfection on the growth of human gastric cancer cell lines. Biochem Biophys Res Commun 1999, 255:753–58.PubMedCrossRef 19. Lue NF: A PF-02341066 mw physical and functional constituent of telomerase anchor site. J Biol Chem 2005,280(28):26586–91.PubMedCrossRef 20. Romero DP, Blackburn EH: A conserved secondary structure for telomerase RNA. Cell 1991,67(2):343–53.PubMedCrossRef 21. Autexier C, Greider CW: Functional reconstitution of wild-type and mutant Tetrahymena telomerase. Genes Dev 1994,8(5):563–75.PubMedCrossRef 22. Fauzi H, Kawakami J, Nishikawa F, Nishikawa S: Analysis of the cleavage reaction of a trans-acting human hepatitis delta virus ribozyme. Nucleic Acids Res 1997,25(15):3124–30.PubMedCrossRef 23. Sirinart A, Perreault JP: Substrate specificity of delta
ribozyme cleavage. J Biol Chem 1998,273(21):13182–88.CrossRef 24. Tomlinson RL, Ziegler TD, Supakorndej T, Terns RM, Terns MP: Cell cycle-regulated trafficking of human telomerase to telomeres. Mol Biol Cell 2006,17(2):955–65.PubMedCrossRef 25. Bailin LIU, Yi QU, Shuqiu LIU, Xuesong Ouyang: Inhibition of telomerase in tumor cells by ribozyme targeting telomerase Metalloexopeptidase RNA component SCIENCE IN CHINA (Series C). 2002,45(1):87–95. 26. Kruk PA, Orren DK, Bohr VA: Telomerase is elevated in early S phase in hamster cells, Biochem. Biophys Res Commun 1997, 233:712–22.CrossRef 27. Griffith JD, Comeau L, Rosenfield S, Stansel RM, Biachi A, Moss H, deLange T: Mammalian telomeres end in a large duplex loop. Cell 1999, 97:503–514.PubMedCrossRef 28. Wyllie FionaS, Jones ChristopherJ, Skinner JuliaW, Haughton MicheleF, Wallis Corrin, Wynford-Thomas David, Faragher RichardGA, Kipling David: Telomerase prevents the accelerated cell aging of Werner syndrome fibroblasts. Nat Genet 2000, 24:16–17.PubMedCrossRef 29. Ren JG, Xia HL, Tian YM, Just T, Cai GP, Dai YR: Expression of telomerase inhibits hydroxyl radical-induced apoptosis in normal telomerase negative human lung fibroblast. FEBS Lett 2001, 488:133–38.PubMedCrossRef 30.