28 These symptoms have been identified as variables that significantly influence the quality of life and are associated with lower adherence to intervention programs for weight control, creating a vicious cycle.29 Thus, the importance of a multidisciplinary team in the treatment of this complex disease is well-established.10 and 14 The quality of life improvement in the physical domain can be associated to the benefits of physical activity in maintaining health,

reflecting the child’s ability to perform everyday activities. The PedsQL questions related to this domain are associated to difficulties in walking, running, playing sports, or feeling low on energy, with difficulties being frequently selleck kinase inhibitor reported by obese children.6 However, after participating in the intervention program, these difficulties were reported less frequently, which may indicate that a healthy occupation during leisure time constitutes an effective means to contribute to a satisfactory quality of life. No effects were observed in the school domain of quality of life after the intervention; however, studies suggest that this domain is not as affected in obese children as the other aspects.6 and 30

The results of the present study demonstrate that a program for the treatment of obesity is associated with improvement in health-related quality of life. However, one study limitation was that other health problems that could interfere with quality of life were not diagnosed, and cultural AT13387 and social factors that could also affect quality of life were not completely controlled in this study. In an attempt to achieve sample homogenization, groups were selected from a single treatment center. Nevertheless, the initial data showed a similarity between the groups in all investigated parameters. The questionnaire was self-reported and the responses

given by the children may not match the reality; in addition, Selleck Sirolimus children may have different interpretations of the intervals determined in PedsQL. The duration of the program effect on HRQoL(Health-Related Quality of Life) and on maintenance of a healthier lifestyle is also unknown. Long-term data related to quality of life have not been well described to confirm this conclusion, and should be interpreted with caution. The results of Duncan et al.15 demonstrated that, despite the health-related quality of life improvement after physical training, the scores were not sustained six weeks after the intervention, which may suggest the need for an ongoing program of intervention for this particular group. The sample loss (27.28%) during the intervention was not expected, and was higher than those of other studies in obese children.